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Extended model predictive control scheme for smooth path following of autonomous vehicles
《机械工程前沿(英文)》 2022年 第17卷 第1期 页码 4-4 doi: 10.1007/s11465-021-0660-4
关键词: autonomous vehicles vehicle dynamic modeling model predictive control path following optimization algorithm
APFD:面向移动轨迹大数据的出租车路径推荐方法 Research Article
陈卫彬1,3,陈杨杨1,2,张亚1,2
《信息与电子工程前沿(英文)》 2022年 第23卷 第10期 页码 1511-1521 doi: 10.1631/FITEE.2100476
本文研究了连续反馈方法在有限时间内同时实现路径跟踪和沿期望轨道编队运动控制的应用。假设虚拟领导者和跟随者之间的拓扑结构是有方向的。设计了一种称为障碍函数的附件条件,使所有智能体在一个有限的区域内移动。首先,基于障碍函数和反步法,设计了一种新型的连续有限时间路径跟踪控制算法。然后,通过将路径跟踪误差视为扰动,设计了一种新型的连续有限时间编队控制算法。详细研究了所得系统的稳定时间特性,并对所提策略进行仿真验证。
Right coronary occlusion following transcatheter aortic valve implantation: two case reports
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《医学前沿(英文)》 2016年 第10卷 第3期 页码 351-355 doi: 10.1007/s11684-016-0465-8
This paper discusses two male patients with severe aortic stenosis, whose right coronary arteries (RCA) were completely occluded during transcatheter aortic valve implantation (TAVI), leading to fatal hemodynamic disorder. Occlusions of RCA complicated by TAVI are rare. In addition, emergency cardiopulmonary bypass (CPB) played a critical role in rescuing our second patient. Both patients were admitted for “severe aortic stenosis,” and TAVIs were performed. The first patient’s blood pressure immediately dropped to 70/40 mmHg after the balloon expansion and did not increase much after the administration of aramine or fluid therapy. He did not receive emergency surgery and died after 1.5 h of resuscitation. The second patient’s blood pressure fluctuated greatly for several minutes after the valve implantation, ranging from 170/100 mmHg to 60/40 mmHg. Angiography revealed a total occlusion of RCA. Thoracic surgery with CPB was performed, and the patient survived.
关键词: aortic stenosis transcatheter aortic valve implantation right coronary occlusion cardiac group
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《医学前沿(英文)》 2017年 第11卷 第4期 页码 471-479 doi: 10.1007/s11684-017-0602-z
Several universal influenza virus vaccine candidates based on eliciting antibodies against the hemagglutinin stalk domain are in development. Typically, these vaccines induce responses that target group 1 or group 2 hemagglutinins with little to no cross-group reactivity and protection. Similarly, the majority of human anti-stalk monoclonal antibodies that have been isolated are directed against group 1 or group 2 hemagglutinins with very few that bind to hemagglutinins of both groups. Here we review what is known about the human humoral immune response to vaccination and infection with H7 subtype influenza viruses on a polyclonal and monoclonal level. It seems that unlike vaccination with H5 hemagglutinin, which induces antibody responses mostly restricted to the group 1 stalk domain, H7 exposure induces both group 2 and cross-group antibody responses. A better understanding of this phenomenon and the underlying mechanisms might help to develop future universal influenza virus vaccine candidates.
关键词: universal influenza virus vaccine hemagglutinin stalk H7N9
ORGANIC CARBON STOCKS IN A SILTY TEXTURED SOIL FOLLOWING REINTEGRATION OF A 20 YEARS OLD × SITE INTO
《农业科学与工程前沿(英文)》 2023年 第10卷 第2期 页码 183-197 doi: 10.15302/J-FASE-2023485
● 0.98 Mg·ha−1·yr−1 Corg accumulation under miscanthus over 26 years.
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《医学前沿(英文)》 2013年 第7卷 第2期 页码 264-269 doi: 10.1007/s11684-013-0259-1
The effect of the severity of appendiceal inflammation on post-operative stay in children following appendicectomy has shown conflicting results. This study was conducted to determine the association between the severity of appendiceal inflammation and post-operative stay amongst children undergoing open appendicectomy. A retrospective cohort study was conducted at a District General Hospital for two years. A total of 204 patients were included in the study with an age range between 3 and 16 years. Females were 54.9% while the rest were male. Mean age was 12.5±3 years. The association of the severity of appendiceal inflammation and post-operative stay was assessed by multivariable Cox Proportional hazards model. Mean post-operative stay was 2.32 days (95% CI 2.14–2.51). Macroscopically perforated appendix, histological inflammation and post-operative complications were significantly associated with post-operative stay on univariable analysis (P<0.05). Whereas, the multivariable analysis showed that the post-operative stay was significantly prolonged only in case of either perforated appendix or post-operative complications while it remained unaffected by the histological inflammation.
关键词: appendiceal inflammation post-operative stay paediatrics
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《医学前沿(英文)》 2017年 第11卷 第1期 页码 68-73 doi: 10.1007/s11684-016-0490-7
This study aims to determine whether successful laparoscopic fundoplication for gastroesophageal reflux disease (GERD) can improve the control of hypertension. We conducted an observational study of GERD patients with hypertension. The esophageal and gastroesophageal symptoms of these patients were successfully treated with laparoscopic fundoplication, as measured by the reduced GERD symptoms and proton pump inhibitor consumption. A hypertension control scale was used to classify the use of antihypertensive medications and the quality of blood pressure control before and after anti-reflux surgery. Wilcoxon signed-ranks test was used for the statistical analyses. Seventy GERD patients were included in the analysis and followed up for a mean period of 3.5±1.4 years. Prior to surgery, all participating patients were taking at least one class of antihypertensive medication, and 56 patients (80%) had intermittently high blood pressure. After surgery, the mean number of antihypertensive medication classes per patient was significantly reduced from 1.61±0.77 pre-procedure to 1.27±0.88 post-procedure (P?<?0.001). The blood pressure of 48 of the 56 cases (86%) with preoperative intermittent high blood pressure returned to normal post procedure. A total of 50 patients (71%) recorded improvements on the hypertension control scale, with the overall mean score decreasing from 3.1±1.0 pre-procedure to 1.4±1.0 post-procedure (P?<?0.001). Therefore, successful laparoscopic fundoplication may result in better blood pressure control in some hypertensive GERD patients. This result suggests a possible connection between gastroesophageal reflux and hypertension.
关键词: gastroesophageal reflux disease hypertension blood pressure laparoscopic fundoplication
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《医学前沿(英文)》 2011年 第5卷 第1期 页码 86-93 doi: 10.1007/s11684-011-0118-x
Netrin-1 (NT-1) is one of the axon-guiding molecules that are critical for neuronal development. Because of its structural homology to the endothelial mitogens, NT-1 may have similar effects on vascular network formation. NT-1 was shown to be able to stimulate the proliferation and migration of human cerebral endothelial cells in vitro and also promote focal neovascularization in adult brain in vivo. In the present study, we reported the delivery of NT-1 using an adeno-associated virus (AAV) vector (AAV-NT-1) into mouse brain followed by transient middle cerebral artery occlusion (tMCAO). We found that AAV vectors did not elicit a detectable inflammatory response, cell loss or neuronal damage after brain transduction. The level of NT-1 was increased in the AAV-NT-1-transduced tMCAO mice compared with the control mice. Furthermore, the neurobehavioral outcomes were significantly improved in AAV-NT-1-transduced mice compared with the control animals (P<0.05) 7 days after tMCAO. Our data suggests that NT-1 plays a neuronal function recovery role in ischemic brain and that NT-1 gene transfer might present a valuable approach to treat brain ischemic disorders.
关键词: adeno-associated virus angiogenesis gene transfer ischemia middle cerebral artery occlusion netrin-1
c-Fos expression in rat brainstem following intake of sucrose or saccharin
Ke Chen, Jianqun Yan, Jinrong Li, Bo Lv, Xiaolin Zhao
《医学前沿(英文)》 2011年 第5卷 第3期 页码 294-301 doi: 10.1007/s11684-011-0144-8
关键词: c-Fos parabrachial the nucleus of the solitary tract sweet tastant rat
谢旭阳,任爱珠
《中国工程科学》 2007年 第9卷 第8期 页码 82-87
用惠更斯原理对震后火灾的动态蔓延过程进行了模拟,并开发了基于GIS的城市地震次生火灾动态蔓延模拟系统,该系统可以模拟单个 或者多个起火点的动态蔓延过程。研究结果可以定量地估计地震次生火灾对城市的危害,从而在最短时间内给救灾应急提供决策依据。
Rise of aluminum-chalcogen batteries: A promising path to sustainable energy storage
《能源前沿(英文)》 2023年 第17卷 第5期 页码 567-568 doi: 10.1007/s11708-023-0887-3
邴红艳
《中国工程科学》 2004年 第6卷 第2期 页码 82-87
文章在简要回顾路径依赖理论的基础上,运用公司治理路径依赖模型:结构驱动路径依赖和制度驱动的路径依赖模型,揭示了公司治理演进过程中路径依赖的作用机理,并针对中国公司治理演进过程中的路径依赖进行了实证分析。
Innovative development path of ethnomedicines: an overview of ethnomedicines in China
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《医学前沿(英文)》 2016年 第10卷 第2期 页码 166-177 doi: 10.1007/s11684-016-0448-9
In the long history of disease prevention and treatment, ancestral populations worldwide have gained knowledge and experiences in traditional medicines. For instance, ethnomedicines of Chinese ethnic minorities constitute an important part of traditional medicines. In our study, we firstly clarified the concept of ethnomedicines and the connotations of ethnopharmacology. The particularity of ethnomedicine research were then summed up, and the development profiles of the ethnomedicines of Chinese ethnic minorities were discussed by investigating the current status and existing problems. On this basis, we abstracted the innovative development path of ethnomedicines for the first time, which was found to follows:resource study → standardized development research → industrialization of the achievements and efforts for internationalization. We found that platform establishment and team training are keys to achieving innovative development. Hence, this study provided a basis for ethnomedicine development.
关键词: traditional medicines ethnomedicines Chinese ethnic minorities ethnopharmacology research mode innovative development path
Study on the Path of “Near-zero Emission” Coal-based Clean Energy Ecosystem Development
Zhang Yu-zhuo
《工程管理前沿(英文)》 2014年 第1卷 第1期 页码 37-41 doi: 10.15302/J-FEM-2014007
关键词: near-zero emission clean energy ecosystem study on the path
Innovative development path of ethnomedicines: the interpretation of the path
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《医学前沿(英文)》 2017年 第11卷 第1期 页码 32-47 doi: 10.1007/s11684-016-0495-2
One of the primary purposes of the innovative development of ethnomedicines is to use their excellent safety and significant efficacy to serve a broader population. To achieve this purpose, modern scientific and technological means should be referenced, and relevant national laws and regulations as well as technical guides should be strictly followed to develop standards and to perform systemic research in producing ethnomedicines. Finally, ethnomedicines, which are applied to a limited extent in ethnic areas, can be transformed into safe, effective, and quality-controllable medical products to relieve the pain of more patients. The innovative development path of ethnomedicines includes the following three primary stages: resource study, standardized development research, and industrialization of the achievements and efforts for internationalization. The implementation of this path is always guaranteed by the research and development platform and the talent team. This article is based on the accumulation of long-term practice and is combined with the relevant disciplines, laws and regulations, and technical guidance from the research and development of ethnomedicines. The intention is to perform an in-depth analysis and explanation of the major research thinking, methods, contents, and technical paths involved in all stages of the innovative development path of ethnomedicines to provide useful references for the development of proper ethnomedicine use.
关键词: ethnomedicines innovative development path resource study standardized development research industrialization internationalization
标题 作者 时间 类型 操作
Right coronary occlusion following transcatheter aortic valve implantation: two case reports
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期刊论文
Universal influenza virus vaccines: what can we learn from the human immune response following exposure
null
期刊论文
ORGANIC CARBON STOCKS IN A SILTY TEXTURED SOIL FOLLOWING REINTEGRATION OF A 20 YEARS OLD × SITE INTO
期刊论文
Appendiceal inflammation affects the length of stay following appendicectomy amongst children: a myth
null
期刊论文
Improved control of hypertension following laparoscopic fundoplication for gastroesophageal reflux disease
null
期刊论文
Overexpression of netrin-1 improves neurological outcomes in mice following transient middle cerebral
null
期刊论文
c-Fos expression in rat brainstem following intake of sucrose or saccharin
Ke Chen, Jianqun Yan, Jinrong Li, Bo Lv, Xiaolin Zhao
期刊论文
Study on the Path of “Near-zero Emission” Coal-based Clean Energy Ecosystem Development
Zhang Yu-zhuo
期刊论文